Professor McArdle graduated with a BSc (Hons) in Biochemistry from the University of Liverpool in 1988 and completed a PhD in the Department of Medicine in 1993. Anne undertook postdoctoral training at the Institute of Gerontology at the University of Michigan and was awarded a Research into Ageing Queen Elizabeth the Queen Mother Fellowship in 1998 to examine the mechanisms by which the age-related failure of muscle to adapt to contractions resulted in sarcopenia. Anne was appointed as Professor in the Faculty of Health and Life Sciences at the University of Liverpool in 2007. She is currently Head of the Department of Musculoskeletal Biology. Anne is past Chair of the British Society for Research on Ageing and the British Council for Ageing. She is an active member of the American Physiological Society where she is International Advisor on the Environmental & Exercise Physiology Steering Committee. Professor McArdle is an Associate Editor for the American Journal of Physiology and a member of the editorial board of Free Radical Biology and Medicine.
Anne has considerable experience of cell and molecular biological studies at the sub-cellular level through to physiological analysis of muscle function in a number of model systems including cell culture, animal models and in humans. The focus of her research is the basic processes by which muscle cells respond and adapt to stress and damage and in particular, the role that the age-related failure in the stress response plays in the development of age-related skeletal muscle dysfunction. Her core research has used genetically modified mice and this has led to a number of key observations in this area of research including the importance of the mitochondrial chaperone system for maintenance of muscle function with age.
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