Bradford Hill is currently an Assistant Professor of Medicine at the University of Louisville (U of L) in Louisville, Kentucky. He received his Ph.D. at U of L and then moved to the University of Alabama-Birmingham to train under Victor Darley-Usmar in the areas of free radical biology and bioenergetics. After post-doctoral training, Dr. Hill was recruited back to U of L, where he currently studies how changes in intermediary metabolism regulate health and disease.
Research Interests:
Dr. Hill’s group focuses on how changes in metabolism contribute to cardiovascular disease. Primarily, he is interested in the role of nutrient excess in regulating vascular insulin resistance and obesity. Mitochondria are particularly sensitive to both nutrient conditions and oxidant-derived stress. Therefore, a general goal of ongoing studies is to determine how environmental conditions leading to obesity affect the function and physiology of mitochondria. This approach involves the use and development of techniques to monitor cellular bioenergetics and metabolism in primary tissues and cells. The long-term objective is to apply knowledge gained from these studies to cultivate new understanding of how to target specific metabolic pathways to prevent or ameliorate cardiovascular diseases caused by obesity and diabetes.
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