Regina Brigelius-Flohé, is professor at the University of Potsdam and heading the Department 'Biochemistry of Micronutrients' at the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE). She received her PhD in Biochemistry in Tübingen and Münster, Germany. During a post-doctoral fellowship in Munich and Düsseldorf together with Helmut Sies she investigated the cellular thiol-disulfide status in perfused organs under various conditions of oxidative stress. The detection and analysis of mixed disulfides of proteins and glutathione provided a basis for the regulation of enzyme activities by thiol modification, a field which is now expanding and known as redox regulation. Her favourized micronutrients at the DIfE are vitamin E and selenium from which the physiological function is still not sufficiently known. Her group was the first to elucidate the metabolism of tocopherols and tocotrienols. At time, her major interests are related to redox-regulated processes in inflammation and cancer development influenced by selenium and specific selenoproteins, mainly glutathione peroxidase 2.
At time her list of publication comprises more than 150 papers. She serves on the editorial board of several journals in the field of nutrition, micronutrients, free radicals, and redox regulation. Dr. Brigelius-Flohé was President of SFRR-Europe 2005/2006.
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