Comments for 19th Biennial Meeting of Society for Free Radical Research International (SFRRI 2018) https://sfrri2018lisbon.organideia.pt/en Mon, 11 Jun 2018 16:05:00 +0000 hourly 1 https://wordpress.org/?v=4.7.10 Comment on Human granulosa cells express proteins of the paraoxonase family by mbego.ruizlarrea https://sfrri2018lisbon.organideia.pt/en/2018/03/06/human-granulosa-cells-express-proteins-of-the-paraoxonase-family-2/#comment-583 Wed, 04 Apr 2018 14:50:16 +0000 https://sfrri2018lisbon.organideia.pt/2018/03/06/human-granulosa-cells-express-proteins-of-the-paraoxonase-family-2/#comment-583 In a previous work, we reported that PONs activities (PON1 paraoxonase and arylesterase, PON2 methyl paraoxonase, and PON3 simvastatinase) were significantly higher in the follicular fluid of large follicles compared with small ones, suggesting that the enzymes have a role in follicle maturation. The findings were found in follicles from both fertile and subfertile women (Meijide et al Reprod Biomed Online 2017). PON1 activities were associated with the number of total oocytes retrieved. Moreover, the activity of PON3 was higher in follicles from fertile women than from patients, suggesting the involvement of the enzyme in fertility.
We also characterized the activities and protein expression of the extracellular PON1 and PON3 proteins in serum and follicular fluid samples obtained from the same woman. The results on PONs expression suggested that the activities determined in follicular fluid did not simply reflect an increased HDL diffusion from the blood through the blood-follicle barrier, but the local synthesis from ovarian cells (Meijide et al Reprod Biomed Online 2017).
The present study confirms the expression of the three enzymes in human granulosa cells, thus being in agreement with our previous results.

]]> Comment on Particulate matters stimulate reactive oxygen species production by a Ca2+ and dual oxidase 2-dependent mechanism in human epidermal keratinocytes by catarina.n.oliveira https://sfrri2018lisbon.organideia.pt/en/2018/03/16/particulate-matters-stimulate-reactive-oxygen-species-production-by-a-ca2-and-dual-oxidase-2-dependent-mechanism-in-human-epidermal-keratinocytes/#comment-572 Fri, 30 Mar 2018 17:21:33 +0000 https://sfrri2018lisbon.organideia.pt/2018/03/16/particulate-matters-stimulate-reactive-oxygen-species-production-by-a-ca2-and-dual-oxidase-2-dependent-mechanism-in-human-epidermal-keratinocytes/#comment-572 Well planned study. However, the identification of ROS produced should be presented.

]]> Comment on Improving arterial surgery outcomes: Combating restenosis with nanotechnology and redox modulation by giovanni.mann https://sfrri2018lisbon.organideia.pt/en/2018/03/16/improving-arterial-surgery-outcomes-combating-restenosis-with-nanotechnology-and-redox-modulation/#comment-531 Sun, 25 Mar 2018 18:53:04 +0000 https://sfrri2018lisbon.organideia.pt/2018/03/16/improving-arterial-surgery-outcomes-combating-restenosis-with-nanotechnology-and-redox-modulation/#comment-531 oral (is this an Early Career Abstract?)

]]> Comment on Resveratrol counteracts inflammation more efficiently than the drug 5-aminosalicylic acid in cytokine-stimulated human intestinal cells by giovanni.mann https://sfrri2018lisbon.organideia.pt/en/2018/02/20/resveratrol-counteracts-inflammation-more-efficiently-than-the-drug-5-aminosalicylic-acid-in-cytokine-stimulated-human-intestinal-cells/#comment-530 Sun, 25 Mar 2018 18:51:20 +0000 https://sfrri2018lisbon.organideia.pt/2018/02/20/resveratrol-counteracts-inflammation-more-efficiently-than-the-drug-5-aminosalicylic-acid-in-cytokine-stimulated-human-intestinal-cells/#comment-530 poster session

]]> Comment on Unravelling the role of DRIF transcription factors in Arabidopsis thaliana by giovanni.mann https://sfrri2018lisbon.organideia.pt/en/2018/02/20/unravelling-the-role-of-drif-transcription-factors-in-arabidopsis-thaliana/#comment-529 Sun, 25 Mar 2018 18:50:25 +0000 https://sfrri2018lisbon.organideia.pt/2018/02/20/unravelling-the-role-of-drif-transcription-factors-in-arabidopsis-thaliana/#comment-529 poster session plant section

]]> Comment on Deregulation of small intestine permeability by miRNA-21 in liver disease by giovanni.mann https://sfrri2018lisbon.organideia.pt/en/2018/02/20/deregulation-of-small-intestine-permeability-by-mirna-21-in-liver-disease/#comment-528 Sun, 25 Mar 2018 18:49:25 +0000 https://sfrri2018lisbon.organideia.pt/2018/02/20/deregulation-of-small-intestine-permeability-by-mirna-21-in-liver-disease/#comment-528 oral session

]]> Comment on Amyloid-β peptide irreversibly blocks mitochondrial biogenesis and dynamics of self-renewing neural stem cells compromising neurogenesis by giovanni.mann https://sfrri2018lisbon.organideia.pt/en/2018/02/20/amyloid-%ce%b2-peptide-irreversibly-blocks-mitochondrial-biogenesis-and-dynamics-of-self-renewing-neural-stem-cells-compromising-neurogenesis/#comment-527 Sun, 25 Mar 2018 18:48:46 +0000 https://sfrri2018lisbon.organideia.pt/2018/02/20/amyloid-%ce%b2-peptide-irreversibly-blocks-mitochondrial-biogenesis-and-dynamics-of-self-renewing-neural-stem-cells-compromising-neurogenesis/#comment-527 poster or oral session

]]> Comment on Molecular determinants of the influenza fusion peptide activity by giovanni.mann https://sfrri2018lisbon.organideia.pt/en/2018/02/20/molecular-determinants-of-the-influenza-fusion-peptide-activity/#comment-526 Sun, 25 Mar 2018 18:47:38 +0000 https://sfrri2018lisbon.organideia.pt/2018/02/20/molecular-determinants-of-the-influenza-fusion-peptide-activity/#comment-526 Poster or oral

]]> Comment on Nitrosopersulfide (SSNO­) is a potential protein Cys polysulfidating agent with sustained and long-range effects by giovanni.mann https://sfrri2018lisbon.organideia.pt/en/2018/02/20/nitrosopersulfide-ssno%e2%80%95-is-a-potential-protein-cys-polysulfidating-agent-with-sustained-and-long-range-effects/#comment-525 Sun, 25 Mar 2018 18:46:02 +0000 https://sfrri2018lisbon.organideia.pt/2018/02/20/nitrosopersulfide-ssno%e2%80%95-is-a-potential-protein-cys-polysulfidating-agent-with-sustained-and-long-range-effects/#comment-525 oral session

]]> Comment on Exploring the role of the bile acid receptor TGR5 in bile acid mediated obesity control: New insights from a CRISPR/Cas9 adipocyte model by giovanni.mann https://sfrri2018lisbon.organideia.pt/en/2018/03/12/exploring-the-role-of-the-bile-acid-receptor-tgr5-in-bile-acid-mediated-obesity-control-new-insights-from-a-crisprcas9-adipocyte-model/#comment-524 Sun, 25 Mar 2018 18:44:32 +0000 https://sfrri2018lisbon.organideia.pt/2018/03/12/exploring-the-role-of-the-bile-acid-receptor-tgr5-in-bile-acid-mediated-obesity-control-new-insights-from-a-crisprcas9-adipocyte-model/#comment-524 oral session

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